| Ballroom C (Washington DC Convention Center) | |||
| The Neurocognitive Effects of Opioids | |||
| The relationships among pain, opioids, and cognitive functioning are complex and poorly understood. Fear of cognitive dysfunction, including sedation, impaired short and long-term attention and memory, decreased reasoning, and prolonged reaction time, hinder clinicians’ willingness to prescribe opioids for chronic pain and patients’ willingness to adhere to treatment. Despite these fears, information about the cognitive effects of opioids from well-designed studies in diverse populations is lacking. To address these deficiencies, this symposium will present findings from three sets of studies examining the cognitive effects of opioids in healthy young, middle-age, and older adults, and patients with cancer-related pain. Dr. Zacny will describe the subjective and psychomotor effects of several oral opioids, including hydrocodone/APAP, oxycodone/APAP, and morphine in a group of young, healthy adults. Dr. Cherrier will report the findings of a randomized, placebo controlled, crossover study comparing the neuropsychological effects of two doses of oral oxycodone on middle-aged and older adults. Dr. Sjogren’s presentation will focus on several studies that have examined the effects of opioids and pain on the cognitive function of cancer patients. | |||
| Moderator: | Robert Jamison, PhD | ||
| Presenters: | Monique Cherrier, PhD James P. Zacny, PhD Per Sjogren, MD, DMSc | ||
| The Neurocognitive Effects of Opioids Robert Jamison, PhD | |||
| Neurocognitive effects of Opioids in Older Adults Monique Cherrier, PhD | |||
| Subjective and Psychomotor Effects of Prescription Opioids in Healthy Young Volunteers James P. Zacny, PhD | |||
| The cognitive effects of opioids and pain in cancer Per Sjogren, MD, DMSc | |||
[Handout]
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